An Index Of Genes Transcribed In The Salivary Glands Of The Ixodid Tick Amblyomma Variegatum

Random clones from a cDNA library made from mRNA purified from dissected salivary glands of feeding female Amblyomma variegatum ticks were subjected to single pass sequence analysis. A total of 3,992 sequences with an average read length of 580 nucleotides have been used to construct a gene index called AvGI that consists of 2,109 non-redundant sequences. A provisional gene identity has been assigned to 39% of the database entries by sequence similarity searches against a non-redundant amino acid database and a protein database that has been assigned gene ontology terms. Homologs of genes encoding basic cellular functions including previously characterised

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Saliva : Systemic Diseases , Systemic Conditions

Salivasaliva : Systemic Diseases

Salivary glands and saliva composition affected directly or indirectly, and these changes may contribute to the diagnosis and early detection of disease.

Abnormal secretions that are present in CF cystic fibrosis causes the physician to explore the usefulness of saliva for disease diagnosis. Most studies agree that the saliva of CF patients contains increased calcium (calcium resulted in aggregation of proteins that cause saliva turbidity and phosphate levels that could explain the higher incidence of calculus, more neutral lipids, phospholipids and glycolipids, as a consequence of physico-chemical properties modified saliva in this disease, the increase in urea, uric acid, and total protein, particularly in the submandibular saliva . Saliva from CF

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