Why Snails Are A Lot Of Saliva / Snail Saliva As Effective as Morphine

To treat severe pain, sea snails may hold the answer. Scientists have developed a new drug was first isolated from the saliva of sea slugs which may be as effective as morphine.
Sea slug can not move fast, but what they lack in speed they more than make up for the chemicals. These animals have the ability to inject a mixture of toxins, called conotoxins fall prey to their targets using their needle-like teeth.
Conotoxins consists of peptides that can relieve severe neuropathic pain as effectively as morphine, but does not cause addiction. Efforts to change this conotoxins into drugs that can be used as a pain reliever has been challenging. As far as synthetic versions have been developed, but must be injected directly into the spinal cord using an implanted pump.
Now, a team of scientists in Australia have developed a conotoxin that can be taken orally. In tests with mice, the new drug proved effective as a pain killer gabapentin, which is the most popular drugs for treating neuropathic pain. Compared with gabapentin doses needed to treat the pain, however, conotoxin-based peptide (called Prialt) is less than 1 percent.

The research team, led by David J. Craik from the Institute for Molecular Bioscience at the University of Queensland, noting that the peptides are generally considered to be poor pain killers because they are unstable and mostly not available in oral form. One exception has immunosuppressant cyclosporine.
Could saliva-based drug next sea snail? Jon-Paul Bignham, a professor of molecular biosciences and bioengineering at the University of Hawaii, Manoa, showed that an oral drug that has the capability of the pain killer Prialt "would actually
revolutionize how we manage chronic pain and terminal "Move over, morphine ..


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Benefits Of Bee Pollen / Royal Jelly

Did you know that bees actually produce 4 kinds of products. Ordinary people only knew honey bee products. But other than honey bees also produce royal jelly, bee pollen, and propolis.
To maintain the health of people usually drink honey, but to treat the disease, propolis is more effective, if using the honey takes a long time and is less efficacious than propolis.
Propolis collected by bees from plants or young shoots and bark of trees, especially poplar and mixed with saliva, which is used to patch holes in the honeycomb honeycomb as well as protecting against viruses, bacteria and fungi.
Propolis is made ​​from the saliva of this bee, proved to be a natural remedy that can be used to conquer almost any type of disease.

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Excessive Drooling Of Children Under Five

Excessive Drooling Of Children Under Five

Is there really a connection between Little frequent drooling, with a mother who wishes not accomplished when cravings? Or, just a little early symptoms will grow teeth? Is drooling constant is indicative of a disease? Let's find out more!  Consider what people comment upon seeing the child salivate continuously. Typically, comments that often arise not far from the myths like, "Wow, she definitely had cravings and not accomplished!" Or any other comments, "Gee, would grow teeth, huh?" Really assumption like that?
Drooling (drooling) or in medical terms is called shalore is something that can be explained scientifically. Dr. Conny Cape, Sp.A of Hospital Pantai Indah Kapuk explain, basically several factors ranging from the physiological to the disorder can cause drooling child.

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About Water Content Of Saliva And Saliva

About Water Content Of Saliva And Saliva

Saliva, saliva, or saliva is a clear liquid produced in the human mouth and some animals. Saliva appeared to have the content of compounds that have various functions for our bodies. Besides, he also has various functions that were previously unknown to us.

Womb
In animals, saliva is produced and secreted from the salivary glands. As for abortion are:
* Electrolytes: (2-21 mmol / L sodium, 10-36 mmol / L potassium, 1.2 to 2.8 mmol / L calcium, 0.08 to 0.5 mmol / L magnesium, 5-40 mmol / L chloride, 2-13 mmol / L bicarbonate, 1.4 to 39 mmol / L phosphate)
* The mucosa, which mainly contain mucopolysaccharide and glycoprotein
* Antibacterial compounds (thiocyanate, hydrogen peroxide, and immunoglobulin A)
* Some kinds of enzymes, including alpha-amylase (EC3.2.1.1), lysozyme (EC3.2.1.17), and lingual lipase (EC3.1.1.3).
Amylase and lipase in a row to start digestion of starch and fat before the food is swallowed. These enzymes work optimally at pH 7.4. Lingual lipase has a pH optimum ~ 4.0, so it will not be active if it has not entered an acidic environment. Lysozyme plays a role in bacterial lysis. Saliva also contains human saliva acid phosphatase A + B (EC3.1.3.2), N-asetilmuramil-L-alanine amidase (EC3.5.1.28), NAD (P) H dehydrogenase-quinone (EC1.6.99.2) , laktoperoksidase saliva (EC1.11.1.7), superoxide dismutase (EC1.15.1.1), glutathione transferase (EC2.5.1.18), class 3 aldehyde dehydrogenase (EC1.2.1.3), glucose-6-phosphate isomerase ( EC5.3.1.9), and tissue kallikrein (EC3.4.21.35). The existence of these products sometimes result in saliva smells.

Humans spend approximately 700 ml of saliva per day.
Some people might find sterile saliva or disinfectant, so believe that saliva will more quickly heal wounds. In fact, the mouth is a hotbed of germs and bacteria. There are over 600 types of bacteria in the mouth and saliva that can cause infection. As quoted from the following MSN secret behind saliva:

What is in saliva
Most of saliva is water, but also contains electrolytes, bacteria, viruses, fungi, secretions from the nose and lungs, cells from the lining of the mouth and about 500 proteins. Of course, the contents of saliva also depends on what you put into the mouth, such as food debris. Components toothpaste also commonly found in saliva. The content of saliva every person is different.
What can be known from saliva?

Of saliva, can be obtained from DNA samples. In fact, although saliva does not contain the DNA of cells, but cells from the lining of the mouth can be found in saliva samples. Saliva is also another clue to the identity of a person's menungkapkan. Saliva may reveal what has been eaten and drugs that may be consumed, such as cocaine, marijuana and barbiturates. Scientists can also use saliva samples to show how much of certain drugs in the body.

The scientists also want to be able to use saliva as a tool to detect the disease, because it is much easier, and in many cases more secure. HIV testing is one of the saliva test which is used as
sample, although the blood test is still the standard way to test for HIV.

What are the functions of saliva
Some people do not realize how important functions of saliva, namely:

• . Break down food in the mouth, so it can be perceived by the tongue and is more easily digested by the stomach.
• . Clean food and dead cells from the lining of the mouth
• . Binds food into a ball so that it can be swallowed
• . Clean food and bacteria from the teeth
• . Prevent dry mouth lining
• . Destroying or preventing the growth of certain fungi
• . Neutralize acids from foods and beverages
• . Help regenerate the damaged tooth enamel, due to calcium and phosphorus levels

How much amount of saliva?
Goodson
estimate the average person produces about half
liters of saliva a day. But of course this number is also
influenced by several factors, among others:

• . Genes
• . Time (saliva production slows down drastically at night)
• . Much water you drink
• . Was chewing gum or sucking hard candy (both increase the production of saliva)
• . Smelling something interesting (also increase saliva production, which is why there is the term 'delicious')
• . More than 400 medications cause a decrease in saliva production
• . Age production (saliva decreases with age)
• . conditions or diseases that affect the production of saliva,
• .such as Sjogren's syndrome, or are undergoing radiation therapy.

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