Infectious diseases
@ : Aliva viral diseases. S is superior to serum and urine for both sensitivity and specificity in testing for HIV infection, human herpes virus, cytomegalovirus, Epstein-Barr virus, hepatitis C virus. The basis for many diagnostic tests in virology is the antibody response to infection. Saliva contains immunoglobulins (Ig) derived from two sources: the salivary glands and serum. The dominant Ig in saliva is secretory IgA (sIgA), which is derived from plasma cells in salivary glands, and are certain key immune defense mechanism in saliva]. In contrast, salivary IgM and IgG mainly derived from serum through GCF, and present in lower concentrations in saliva than IgA. Antibodies against viruses and viral components can be detected in saliva and may assist in the diagnosis of
